Reply 1 and 2 by 04/21/2022 at 5 pm

 reply 1

   Drugs affecting the hematopoietic system can be categorized three classes: oral anticoagulants such as warfarin, antiplatelets such aspirin, and hematopoietic growth factors such as filgrastim. Oral anticoagulants inhibit the synthesis of vitamin K-dependent clotting factors X, IX, VII, and II. Antiplatelets inhibits cyclooxygenase, interferes with platelet aggregation; reduces platelet aggregation by inhibiting adenosine diphosphate pathway; protease-activated receptor-I antagonist, inhibits thrombin. Hematopoietic growth factors stimulate erythropoiesis and is used for the treatment of anemia; stimulate granulocyte formation and is used for neutropenia secondary to bone cancer and chemotherapy (Woo &Robinson, 2020).

            Warfarin is one of the most widely used oral anticoagulant medications which is reduces the formation of blood clots. Warfarin is used to treat deep vein thrombosis and pulmonary embolism or prevent blood clots in veins or arteries which can reduce the risk of stroke, heart attack in the patients who have high risk of having them in the future. Warfarin dosing regimen will be calculated or individualized for the patient by the clinician using warfarin dosing calculator (warfarindosing, n.d.). Warfarin should be taken at the same time every day, never take a double dose. INR/PT test should be monitored, the patients who take warfarin must remain under the doctor care while taking it (, 2022).

            Aspirin is in a group of medications called salicylates; it is one of the antiplatelets. Aspirin works by stopping the production of certain natural substances that cause fever, pain swelling and blood clots. Aspirin is widely used as antiplatelet medication in secondary prevention to prevent heart attacks or stroke and can be consumed 81 mg, 1 p.o. daily. Statistical analysis of aspirin in patients after myocardial infarction was done by Stolarek et al. (2022)., they state that routine test should be done as well as anti-plate treatment effects. If missed the dose and it is almost time for the next dose, skip the missed dosed and continue the regular schedule. Do not take double dose to make up missed dose. A salicylates level test is most often used to evaluate aspirin poisoning, CBC should be monitoring too (Woo & Robinson, 2020).

            Filgrastim usually given SQ, the brand name is neupogen. It is man-made form of granulocyte colony-stimulating factor(G-CSF). G-CSF is a substance produced by the body. It stimulates the growth of neuropils which is one of white blood cells fighting against infection. Filgrastim used myelosuppressive chemotherapy give through subcutaneous (300mcg/ml ) 5mcg/kg/d no earlier than 24 hours before next dose of chemotherapy, dose given  daily for up to 2 weeks, discontinue if ANC >10000 mm3 after expected nadir or chemotherapy. CBC counts must monitored closely (Woo & Robinson, 2020).

Calculate the price of your order

550 words
We'll send you the first draft for approval by September 11, 2018 at 10:52 AM
Total price:
The price is based on these factors:
Academic level
Number of pages
Basic features
  • Free title page and bibliography
  • Unlimited revisions
  • Plagiarism-free guarantee
  • Money-back guarantee
  • 24/7 support
On-demand options
  • Writer’s samples
  • Part-by-part delivery
  • Overnight delivery
  • Copies of used sources
  • Expert Proofreading
Paper format
  • 275 words per page
  • 12 pt Arial/Times New Roman
  • Double line spacing
  • Any citation style (APA, MLA, Chicago/Turabian, Harvard)

Our guarantees

Delivering a high-quality product at a reasonable price is not enough anymore.
That’s why we have developed 5 beneficial guarantees that will make your experience with our service enjoyable, easy, and safe.

Money-back guarantee

You have to be 100% sure of the quality of your product to give a money-back guarantee. This describes us perfectly. Make sure that this guarantee is totally transparent.

Read more

Zero-plagiarism guarantee

Each paper is composed from scratch, according to your instructions. It is then checked by our plagiarism-detection software. There is no gap where plagiarism could squeeze in.

Read more

Free-revision policy

Thanks to our free revisions, there is no way for you to be unsatisfied. We will work on your paper until you are completely happy with the result.

Read more

Privacy policy

Your email is safe, as we store it according to international data protection rules. Your bank details are secure, as we use only reliable payment systems.

Read more

Fair-cooperation guarantee

By sending us your money, you buy the service we provide. Check out our terms and conditions if you prefer business talks to be laid out in official language.

Read more

STAY HOME, SAVE LIVES. Order your essay today and save 20% with the discount code ATOM